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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 5.76
Human Site: S1406 Identified Species: 11.52
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S1406 P A A P G R H S S S L S N V L
Chimpanzee Pan troglodytes XP_525997 2750 313008 E1411 L S G I D S C E M S D S G S Q
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 L1005 R G Q L F L L L F E P G N A D
Dog Lupus familis XP_541900 2305 251162 Q1015 R L P E R S R Q R L R L R E Y
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S1402 P T A Q G R H S S S L S N V L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 Q979 A V Q L L I E Q V S V E K N M
Chicken Gallus gallus XP_421964 2298 259902 S1008 G T H E E I Q S I V G Y I A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 Q1716 F K W S Y I H Q R L L S D V L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 A1204 R Q S L R I S A T V T V R H I
Sea Urchin Strong. purpuratus XP_785921 3355 375569 D2031 T E S T L S I D T P D D S S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 W1495 W K Y R S R L W Y G V G L P S
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 Y877 V F D P K K S Y V M V S L L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 13.3 6.6 0 N.A. 86.6 N.A. N.A. 6.6 6.6 N.A. N.A. N.A. 33.3 N.A. 0 0
P-Site Similarity: 100 20 6.6 0 N.A. 86.6 N.A. N.A. 20 6.6 N.A. N.A. N.A. 40 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 17 0 0 0 0 9 0 0 0 0 0 17 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 9 0 0 9 0 0 17 9 9 0 17 % D
% Glu: 0 9 0 17 9 0 9 9 0 9 0 9 0 9 0 % E
% Phe: 9 9 0 0 9 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 9 9 0 17 0 0 0 0 9 9 17 9 0 0 % G
% His: 0 0 9 0 0 0 25 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 9 0 34 9 0 9 0 0 0 9 0 17 % I
% Lys: 0 17 0 0 9 9 0 0 0 0 0 0 9 0 0 % K
% Leu: 9 9 0 25 17 9 17 9 0 17 25 9 17 9 25 % L
% Met: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 25 9 0 % N
% Pro: 17 0 9 17 0 0 0 0 0 9 9 0 0 9 0 % P
% Gln: 0 9 17 9 0 0 9 25 0 0 0 0 0 0 9 % Q
% Arg: 25 0 0 9 17 25 9 0 17 0 9 0 17 0 0 % R
% Ser: 0 9 17 9 9 25 17 25 17 34 0 42 9 17 9 % S
% Thr: 9 17 0 9 0 0 0 0 17 0 9 0 0 0 0 % T
% Val: 9 9 0 0 0 0 0 0 17 17 25 9 0 25 0 % V
% Trp: 9 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 9 0 0 9 9 0 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _